IGNOU BCHET-149 December 2024 Previous Year Question Paper

Q1.(a) Fillin the blanks : 5 @) Fatty acid biosynthesis takes place Gi) The cofactor of enzyme acetyl-CoA

(iii) Oxidative deamination is catalysed by an enzyme called eee «

(iv) Hydrogen peroxide is decomposed by the enzyme ou... eee =

(v) D-glucose on reaction with nitric acid QIVES veces =

(b) Why is sucrose a non-reducing sugar while maltose is a reducing sugar ? Explain.

Q2.(a) Describe the classification of amino acids on the basis of their chemical composition. 5

(b) Define isoelectric point. Explain the titration curve of Glycine.

Q3.Explain any two of the following : 5+5

(a) Why is cellulose insoluble in water and why is it not used as an energy source by humans ?

(b) Why is the peptide bond planar ?

(c) Why are enzymes effective drug targets ?

Q4.Define the following terms with suitable examples : 2 each

(a) Enantiomer

(b) Diastereomer

(c) Anomer

(d) Mutarotation

Q5.(a) Write True or False for the following statements : 5

(i) Albumin is soluble in water and in salt solution.

(ii) Collagen is an example of a fibrous protein. @ii) Formation of DNA is catalysed by DNA polymerase.

(iv) The characteristic of the genetic material is not to duplicate.

(v) Presence of higher than normal quantities of ketone bodies in blood is called ketonurea.

(b) What are drugs ? What is the role of SAR studies in drug development ?

Q6.Describe any two of the following with a suitable diagram : 5+5

(a) TCA cycle

(b) Urea cycle

(c) Merrifield solid phase synthesis of peptides

Q7.Write short notes on any two of the following : 5+5

(a) Biological functions of proteins

(b) Isoenzymes

(c) Insulin

Q8.(a) Describe in brief the structure and functions of haemoglobin. 5

(b) How does pH affect the enzyme activity in the biological systems ? Explain with a suitable example. 5 5+5 (#) TCA WH